2023
- Interplay between mechanochemical patterning and glassy dynamics in cellular monolayers
D. Boocock, T. Hirashima, E. Hannezo, PRXLife (2023) - Temporal variability and cell mechanics control robustness in mammalian embryogenesis
D. Fabreges*, B. Corominas-Murtra*, … , E. Hannezo* & T. Hiiragi*, BioRxiv - Chiral and nematic phases of flexible active filaments
Z. Dunajova*, B. Mateu*, … , E. Hannezo* & M. Loose*, Nat Phys, 1-11 (2023) - Cell cycle dynamics controls fluidity of the developing mouse neuroepithelium
L Bocanegra-Moreno, A Singh, E Hannezo, M Zagorski, A Kicheva, Nat Phys (2023) - Sinking the way: a dual role for CCR7 in collective leukocyte migration
J Alanko, MC Ucar, …, E. Hannezo* and M Sixt*, Sci Immuno, (2023) - Unconventional colloidal aggregation in chiral bacterial baths
D Grober, I Palaia, MC Uçar, E Hannezo, A Šarić, J Palacci Nature Physics, 1-9 (2023) - Adhesion-induced cortical flows pattern E-cadherin-mediated cell contacts
FN Arslan, E Hannezo, J Merrin, M Loose, CP Heisenberg, Curr Biol, (2023) - Self-organized and directed branching results in optimal coverage in developing dermal lymphatic networks
MC Ucar*, E Hannezo*, …, K Vaahtomeri, Nat Comm, 14 (1), 5878 (2023)
2022
- Modelling the dynamics of mammalian gut homeostasis
B Corominas-Murtra*, E Hannezo*, Seminars in Cell & Developmental Biology - Retrograde movements determine effective stem cell numbers in the intestine
M Azkanaz°, B Corominas-Murtra°, …, E Hannezo*, J van Rheenen* Nature, 607 (7919), 548-554 (2022) - Morphogen gradient orchestrates pattern-preserving tissue morphogenesis via motility-driven unjamming
D Pinheiro, R Kardos, E Hannezo*, CP Heisenberg*, Nat Phys (2022)
News & Views: Unjammed development
Dispatch: Nodal signaling controls ordered collective cell migration - Geometry-driven migration efficiency of minimal cell clusters
E Vercruysse°, DB Brückner°, …, E. Hannezo* and S. Gabriele*, bioRxiv, (2022) - Multitier mechanics control stromal adaptations in the swelling lymph node
F Assen et al, Nat Immuno, 1-10 (2022) - Dual role of Pectin Methyl Esterase activity for plant cell growth regulation
Gallemi et al, BioRxiv, 10.1101/2022.06.14.495617 - Spatiotemporal dynamics of self-organized branching in pancreas-derived organoids
S Randriamanantsoa et al, Nat Comm (2022) - Cell surface fluctuations regulate early embryonic lineage sorting
A Yanagida, E Corujo-Simon, CK Revell, P Sahu, …, E. Hannezo, EK Paluch, J Nichols, KJ Chalut, Cell, 185 (5), 777-793 (2022) - A self-generated Toddler gradient guides mesodermal cell migration
J Stock, T Kazmar, F Schlumm, E Hannezo*, A Pauli*, Sci Adv, 8 37 (2022) - Rigidity transitions in development and disease
E Hannezo*, CP Heisenberg*, Trend Cell Biol (2022)
2021
- Geometry adaptation of protrusion and polarity dynamics in confined cell migration
DB Brückner, …, E. Hannezo, J. Radler and CP Broedersz, Phys Rev X 12 (3), 031041 (2021) - Extracellular hyaluronate pressure shaped by cellular tethers drives tissue morphogenesis
A. Munjal*, E. Hannezo, T. Tsai, T. Mitchinson and S. Megason*, Cell, 184 (26), 6313-6325. e18 (2021) - Theory of branching morphogenesis by local interactions and global guidance
MC. Ucar°, D. Kamenev°, …, S. Hadjab* and E. Hannezo* , Nat Comm (2021) - Large-scale curvature sensing by epithelial monolayers depends on active cell mechanics and nuclear mechanoadaptation
M. Luciano°, S.L. Xue°, …, E. Hannezo* and S. Gabriele*, Nat Phys, 17 (12), 1382-1390 (2021)
Prelight: Sensing the curve - Rigidity percolation uncovers a structural basis for embryonic tissue phase transitions
N. Petridou°, B. Corominas-Murtra°, CP Heisenberg* and E. Hannezo*, Cell, 184, 7 (2021)
Recommendations: F1000 - Constrained actin dynamics emerges from variable compositions of actin regulatory protein complexes
U. Dobramysl, … E. Hannezo, B.D. Simons and J. Gallop, JCB, 220-4 (2021) - Cell fate coordinates mechano-osmotic forces in intestinal crypt morphogenesis
Q. Yang*°, S.-L. Xue°, … , E. Hannezo* and P. Liberali*, Nat Cell Biol, 1-12 (2021) - Roadmap for the multiscale coupling of biochemical and mechanical signals during development
PF Lenne et al, Physical Biology 18 (4), 041501 (2021) - DoUble resin Casting micro computed Tomography (DUCT) reveals biliary and vascular pathology in a mouse model of Alagille syndrome
S Hankeova… , E. Hannezo, J. Kaiser and E. Anderson, eLife, 10, e60916 (2021)2020
- Tracing the cellular basis of islet specification in mouse pancreas
M.K. Sznurkowska°, E. Hannezo°, R. Azzarelli, …, A. Philpott* and B. Simons*, Nat. Comm , 11, 5037 (2020) - Theory of mechano-chemical patterning and optimal migration in cell monolayers
D. Boocock°, N. Hino°, N. Ruzickova, T. Hirashima* and E. Hannezo*, Nat. Phys, (2020)
Press commentary: Der Standard Phys.org - Stem cell lineage survival as a noisy competition for niche access
B. Corominas-Murtra*°, C. Scheele°, K Kishi, SIJ Ellenbroek, BD Simons, J. Van Rheenen*, E. Hannezo*, PNAS, 17 (29) 16969-16975 (2020) - Abscission couples cell division to embryonic stem cell fate
A. Chaigne, …, E. Hannezo, K. Chalut and E. Paluch, Dev Cell, (2020) - Defining the Design Principles of Skin Epidermis Postnatal Growth
S Dekoninck°, E Hannezo°, … , BD Simons, C. Blanpain, Cell, 181, 3 (2020)
2019
- Tracing the cellular basis of islet specification in mouse pancreas
- Active cell migration is critical for steady-state epithelial turnover in the gut
D. Krndija*, …, Y. Bellaiche, E. Hannezo* and D. Vignjevic*, Science (2019)
Highlight: Cryptic migration
Dispatch: Active Migration of Intestinal Epithelial Cells in Tissue Renewal
Perspective: Marching out of the crypt
Recommendations: F1000 - Mechano-chemical feedback loops in morphogenesis and disease
E. Hannezo* and CP Heisenberg*, Cell (2019) - Multiscale dynamics of branching morphogenesis
E. Hannezo* and B. Simons*, Curr. Op. Cell Bio., (2019) - Tracing the cellular dynamics of sebaceous gland development in normal and perturbed states
M. Andersen°, E. Hannezo°, …, B. Simons*, K. Jensen*, Nat Cell Bio, (2019)
Perspective: Equal opportunities in stemness - Tracing the origin of adult intestinal stem cells
J. Guiu°, E. Hannezo°, …, B. Simons*, K. Jensen*, Nature, (2019)
Perspective: Equal opportunities in stemness
European Scientist: All immature cells of the gut can become intestinal stem cells - Bulk Actin Dynamics Drive Phase Segregation in Zebrafish Oocytes
S. Shamipour, R. Kardos, S.-L. Xue, B. Hof, E. Hannezo* and C.-P. Heisenberg*, Cell, (2019)
Perspective: Cellular Organization: Bulk Actin Network Flows Drive Ooplasm Segregation - Theory of mechano-chemical patterning in biphasic biological tissues
P. Recho°*, A. Hallou°* and E. Hannezo°*, PNAS, (2019)
Recommendation: F10002018
- Fluidization-mediated tissue spreading by mitotic cell rounding and non-canonical Wnt signalling.
NI Petridou, S Grigolon, G Salbreux, E Hannezo, CP Heisenberg, Nat Cell Biol (2018)
Commentary: The fluid fish - Zipf’s law, unbounded complexity and open-ended evolution
B Corominas-Murtra, LF Seoane, R Solé, Interface (2018) - Defining Lineage Potential and Fate Behavior of Precursors during Pancreas Development.
M.K. Sznurkowska, E. Hannezo, R. Azzarelli, … & B. Simons, Dev. Cell (2018) - A Toy Model for Active Interfaces.
E Hannezo, Physics, (2018) - Clonal analysis of Notch1 cells reveals the existence of unipotent stem cells that retain long-term plasticity in the embryonic mammary gland.
A. M. Lilja°, V. Rodilla°, M. Huyghe, E. Hannezo, … , B. Simons, and S. Fre, Nat Cell Biol, (2018)
Commentary: Mammary lineage restriction in development - A biochemical network controlling basal myosin oscillation.
Qin. X°, E. Hannezo°, Mangeat T., … and Wang X. Nature Comm, (2018)
CNRS press release - Theory of epithelial cell shape transitions induced by mechanoactive chemical gradients.
K. Dasbiswas, E. Hannezo and N. Gov, Biophys. J., 114(4) 968-977. (2018)2017
- A unifying theory of branching morphogenesis.
E. Hannezo*°, C. Scheele°, M. Moad, N. Drogo, R. Heer, R. Sampogna, J. Van Rheenen and B. Simons*, Cell, 171(1), 242-255, (2017)
Commentary: Scientists reveal the “beautiful” simplicity underlying branching patterns in tissue
Naked Scientist podcast: How do tissues grow? - Multipotent basal stem cells support directed large-scale epithelial flows in adult human prostate.
M. Moad°, E. Hannezo°, S. Buczacki, L., … , B. Simons* and R. Heer*, 20(7), 1609-1622, Cell Reports, (2017)
Recommendation: F1000 - Transmission of cytokinesis forces via E-Cadherin dilution and actomyosin flows
D. Pinheiro, E. Hannezo°, S. Herstzerg°, … and Y. Bellaiche, Nature, 545 (7652), 103-107 (2017)
Recommendation: F1000 - Identity and dynamics of mammary stem cells during branching morphogenesis.
C. Scheele°, E. Hannezo°, M. Muraro, A. Zomer, N. Langedijk, A. van Oudenaarden, B. Simons* and J. Van Rheenen*, Nature, 542, 313-317 (2017)
Preview: Un(MaSC)ing Stem Cell Dynamics in Mammary Branching Morphogenesis - RhoA regulates actin network dynamics during apical emergence in multiciliated cells. J. Sedzinski, E. Hannezo, F. Tu, M. Biro and J. Wallingford, J Cell Sci, 130(2):420- 42 (2017)
2010-2016
- Defining the clonal dynamic leading to basal cell carcinoma initiation.
A. Sanchez-Danes°, E. Hannezo°, J.-C. Larsimont, M. Liagre, K. Youssef , B. Simons* and C. Blanpain*, Nature, 536(7616), 298-303, (2016)
Commentary: Where did it all go wrong?, RT news - Interplay of migratory and division forces as a generic mechanism for stem cell patterns.
E. Hannezo, A. Coucke and J-F. Joanny, Phys. Rev. E, 93(2), 022405. (2016) - Emergence of an apical epithelial cell surface in vivo.
J. Sedzinski°, E. Hannezo°, F. Tu, M. Biro and J. Wallingford, Dev. Cell, 36 (1),24-35, (2016)
Recommendation: F1000 - Physics of active jamming during collective cellular motion in a monolayer.
S. Garcia, E. Hannezo, J. Elgeti J-F. Joanny, P. Silberzan, N. Gov, PNAS, 112 (50), 15314-15319, (2015) - Assembly and positioning of actomyosin rings by contractility and PCP
I. Sehring, P. Recho, E. Denker, M. Kourakis, B. Mathiesen, E. Hannezo*, B. Dong*, D. Jiang*, eLife, 4:e09206., (2015)
Recommendation: F1000 - A cortical instability drives supracellular actin ring formation in biological tubes.
E. Hannezo°*, B. Dong°, P. Recho, J-F. Joanny and S. Hayashi*, PNAS, 04762, (2015)
Perspective: Three-ring circus without a ringmaster
- Dynamic model of Heat Transfer in an porous wick of Capillary Pumped Loop.
R. Boubaker, V. Platel, A. Berges, M. Bancelin, E. Hannezo, App. Therm. Eng., 76, 1-8 (2014) - Balance between Apical Growth and Matrix Resistance Determines Epithelial Tubule Shape.
B. Dong, E. Hannezo, S. Hayashi, Cell reports, 7(4), 941-950 (2014) - Homeostasis and dynamics of stem-cell tissues.
E. Hannezo*, J-F Joanny and J. Prost, J. R. Soc. Interface, 11 (93), 20130895 (2014) - Theory of epithelial sheet morphology in three dimensions.
E. Hannezo*, J-F Joanny and J. Prost, PNAS 111 (1), 27-32 (2013) - Alignment of cellular motility forces with flow as a mechanism for efficient wound healing.
M. Basan, J. Elgeti, E. Hannezo, W-J Rappel and H. Levine, PNAS (2013) - Mechanical instabilities of biological tubes.
E. Hannezo, J-F Joanny and J. Prost, PRL 109, 018101 (2012) - Instabilities of Monolayered Epithelia: Shape and Structure of Villi and Crypts.
E. Hannezo, J-F Joanny and J. Prost, PRL 107, 078104 (2011)
Editors’ suggestion
Synopsis: Know when to fold ’em - Notch Lineages in Intestinal Stem Cells Determined by A New Set of Knock-In Mice.
S. Fre, E. Hannezo, S. Sale, M. Huyghe, … , S. Artavanis-Tsakonas, PLoS ONE 6(10) : e25785 (2011) - Glass-like dynamics of collective cell migration.
T. Angelini, E. Hannezo, X. Trepat, J. Fredberg and D. Weitz, PNAS, 4714-4719 (2011)
News: We’re made of glass
Commentary: Dynamic heterogeneity comes to life - Cell Migration Driven by Cooperative Substrate Deformation Patterns
T. Angelini, E. Hannezo, X. Trepat, J. Fredberg and D. Weitz, PRL 104, 168104 (2011)
°: First authors
*: Corresponding authors